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Genetic Disorders

Among Ashkenazi Jews, a higher incidence of specific hereditary diseases has been reported:

Genetic counseling and genetic testing are recommended for couples where both partners are of Ashkenazi ancestry. Some organizations organize screening programs to prevent homozygosity for the genes that cause these diseases. See Jewish Genetics Center for more information on testing programmes.

 

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JEWISH
(Ashkenazi)

 

Excerpts from Wikipedia.org

Ashkenazi Jews (Standard Hebrew: sing. אַשְׁכֲּנָזִי, pl. אַשְׁכֲּנָזִים) are descended from the medieval Jewish communities of the Rhineland, "Ashkenaz" being the Medieval Hebrew name for Germany.

Many later migrated, largely eastward, forming communities in Germany, Hungary, Poland, Russia, Eastern Europe and elsewhere between the 10th and 19th centuries. From medieval times the lingua franca among Ashkenazi Jews was Yiddish or, to a much lesser extent, the Judæo-French language Zarphatic, the Slavic-based Knaanic (Judæo-Czech), and to some speakers of the recently extinct (since 1977) Judæo-Provençal language, Shuadit, (all three no longer spoken). The Ashkenazi Jews developed a distinct culture and liturgy influenced, to varying degrees, by interaction with surrounding peoples, predominantly Germans, Poles, Czechs, Slovaks, Kashubians, Hungarians, Ukrainians, Lithuanians, Letts, Belarusians, and Russians.

Although in the 11th century they comprised only 3% of the world's Jewish population, Ashkenazi Jews accounted for (at their highest) 92% of the world's Jews in 1931 and today make up approximately 80% of Jews worldwide. Most Jewish communities with extended histories in Europe are Ashkenazim, with the exception of those associated with the Mediterranean region. A significant portion of the Jews who migrated from Europe to other continents in the past two centuries are Eastern Ashkenazim, particularly in the United States (which has the largest Ashkenazi population in the world).

 

Ethnic Definition

In an ethnic sense, an Ashkenazi Jew is one whose ancestry can be traced to the Jews of central and eastern Europe. For roughly a thousand years, the Ashkenazi were a reproductively isolated population in Europe, despite living in many countries, with little inflow or outflow from migration, conversion, or intermarriage with other groups, including other Jews. Human geneticists have identified genetic variations that have high frequencies among Ashkenazi Jews, but not in the general European population. This is true for patrilineal markers (Y-chromosome haplotypes) as well as for matrilineal markers (mitochondrial haplotypes).

A study by Michael Seldin, a geneticist at the University of California Davis School of Medicine, found Ashkenazi Jews to be a clear, relatively homogenous genetic subgroup. Strikingly, regardless of the place of origin, Ashkenazi Jews can be grouped in the same genetic cohort — that is, regardless of whether an Ashkenazi Jew's ancestors came from Poland, Russia, Hungary, Lithuania, or any other place with a historical Jewish population, they belong to the same ethnic group. The research demonstrates the endogamy of the Jewish population in Europe and lends further credence to the idea of Ashkenazi Jews as an ethnic group. Moreover, though intermarriage among Jews of Ashkenazi descent has become increasingly more common, many Ultra-Orthodox Jews, particularly members Hasidic or Hareidi sects, continue to marry exclusively fellow Ashkenazi Jews. This trend keeps Ashkenazi genes prevalent and will also help researchers further study the genes of Ashkenazi Jews with relative ease. It is also noteworthy that these Ultra-Orthodox Jews often have extremely large families too.

 

Origins of Ashkenazim

Although the historical record itself is very limited, there is a consensus of cultural, linguistic, and genetic evidence that the Ashkenazi Jewish population originated in the Middle East. When they arrived in northern France and the Rhineland sometime around 800-1000 CE, the Ashkenazi Jews brought with them both Rabbinic Judaism and the Babylonian Talmudic culture that underlies it. Yiddish, once spoken by the vast majority of Ashkenazi Jewry, is a Jewish language which developed from the Middle High German vernacular, heavily influenced by Hebrew and Aramaic. (By comparison, the Greek or Latin influence on Yiddish was much less significant).

European Jews came to be called "Ashkenaz" because the main centers of Jewish learning were located in Germany.

 

Background in the Roman Empire

After the forced Jewish exile from Jerusalem in 70 AD and the complete Roman takeover of Judea following the Bar Kochba rebellion of 132-135 ADE, Jews continued to be a majority of the population in Palestine for several hundred years. However, the Romans no longer recognized the authority of the Sanhedrin or any other Jewish body, and Jews were prohibited from living in Jerusalem. Outside the Roman Empire, a large Jewish community remained in Mesopotamia. Other Jewish populations could be found dispersed around the Mediterranean region, with the largest concentrations in the Levant, Egypt, Asia Minor, Greece, and Italy, including Rome itself. Smaller communities are recorded in southern Gaul (France), Spain, and North Africa.

Jews were denied full Roman citizenship until 212 AD, when Emperor Caracalla granted all free peoples this privilege. However as a penalty for the first Jewish Revolt, Jews were still required to pay a poll tax until the reign of Emperor Julian in 363 AD. In the late Roman Empire, Jews were still free to form networks of cultural and religious ties and enter into various local occupations. But after Christianity became the official religion of Rome and Constantinople, Jews were increasingly marginalized, and brutally persecuted.

In Palestine and Mesopotamia, where Jewish religious scholarship was centered, the majority of Jews were still engaged in farming, as demonstrated by the preoccupation of early Talmudic writings with agriculture. In diaspora communities, trade was a common occupation, facilitated by the easy mobility of traders through the dispersed Jewish communities.

Throughout this period and into the early Middle Ages, many Jews assimilated into the dominant Greek and Latin cultures, mostly through conversion to Christianity. In Palestine and Mesopotamia, the spoken language of Jews continued to be Aramaic, but elsewhere in the diaspora, most Jews spoke Greek. Conversion and assimilation were especially common within the Hellenized or Greek-speaking Jewish communities, amongst whom the Septuagint and Aquila of Sinope (Greek translations and adaptations of the Tanakh or Hebrew Bible) were the source of scripture. A remnant of this Greek-speaking Jewish population (the Romaniotes) survives to this day.

The Germanic invasions of the Western Roman Empire in the 5th century by tribes such as the Visigoths, Franks, Lombards, and Vandals caused massive economic and social instability within the western Empire, contributing to its decline. In the late Roman Empire, Jews are known to have lived in Cologne and Trier, as well as in what is now France. However, it is unclear whether there is any continuity between these late Roman communities and the distinct Ashkenazi Jewish culture that began to emerge about 500 years later. King Dagobert of the Franks expelled the Jews from his Merovingian kingdom in 629. Jews in former Roman territories now faced new challenges as harsher anti-Jewish Church rulings were enforced.

 

Rabbinic Judaism Moves to Ashkenaz

In Mesopotamia, and in Persian lands free of Roman imperial domination, Jewish life fared much better. Since the conquest of Judea by Nebuchadrezzar II, this community had always been the leading diaspora community, a rival to the leadership of Palestine. After conditions for Jews began to deteriorate in Roman controlled lands, many of the religious leaders of Judea and the Galilee fled to the east. At the academies of Pumbeditha and Sura near Babylon, Rabbinic Judaism based on Talmudic learning began to emerge and assert its authority over Jewish life throughout the diaspora. Rabbinic Judaism created a religious mandate for literacy, requiring all Jewish males to learn Hebrew and read from the Torah. This emphasis on literacy and learning a second language would eventually be of great benefit to the Jews, allowing them to take on commercial and financial roles within Gentile societies where literacy was often quite low.

After the Islamic conquest of the Middle East and North Africa, new opportunities for trade and commerce opened between the Middle East and Western Europe. The vast majority of Jews in the world now lived in Islamic lands. Urbanization, trade, and commerce within the Islamic world allowed Jews, as a highly literate people, to abandon farming and live in cities, engaging in occupations where they could use their skills. The influential, sophisticated, and well organized Jewish community of Mesopotamia, now centered in Baghdad, became the center of the Jewish world. In the Caliphate of Baghdad, Jews took on many of the financial occupations that they would later hold in the cities of Ashkenaz. Jewish traders from Baghdad began to travel to the west, renewing Jewish life in the western Mediterranean region. They brought with them Rabbinic Judaism and Babylonian Talmudic scholarship.

After 800 AD, Charlemagne's unification of former Frankish lands with northern Italy and Rome brought on a brief period of stability and unity in Western Europe. This created opportunities for Jewish merchants to settle once again north of the Alps. Charlemagne granted the Jews in his lands freedoms similar to those once enjoyed under the Roman Empire. Returning once again to Frankish lands, many Jewish merchants took on occupations in finance and commerce, including moneylending or usury. (Church legislation banned Christians from lending money in exchange for interest.) From Charlemagne's time on to the present, there is a well documented record of Jewish life in northern Europe, and by the 11th century, when Rashi of Troyes wrote his commentaries, Ashkenazi Jews had emerged also as interpreters and commentators on the Torah and Talmud.

 

Ashkenazi Migrations Throughout the High and Late Middle Ages

Historical records show evidence of Jewish communities north of the Alps and Pyrenees as early as the 8th and 9th century. By the early 900s, Jewish populations were well-established in Northern Europe, and later followed the Norman Conquest into England in 1066, also settling in the Rhineland. With the onset of the Crusades, and the expulsions from England (1290), France (1394), and parts of Germany (1400s), Jewish migration pushed eastward into Poland, Lithuania, and Russia. Over this period of several hundred years, some have suggested, Jewish economic activity was focused on trade, business management, and financial services, due to Christian European prohibitions restricting certain activities by Jews, and preventing certain financial activities (such as "usurious" loans) between Christians.

By the 1400s, the Ashkenazi Jewish communities in Poland were the largest Jewish communities of the diaspora. Poland in this time was a decentralized medieval monarchy, incorporating lands from Latvia to Romania, including much of modern Lithuania and Ukraine. This area, which eventually fell under the domination of Russia, Austria, and Prussia (Germany), would remain the main center of Ashkenazi Jewry until the Holocaust.

 

Ashkenazi Jews and the Holocaust

Of the estimated 8.8 million Jews living in Europe at the beginning of World War II, the majority of whom were Ashkenazi, about 6 million — more than two-thirds — were systematically murdered in the Holocaust. These included 3 million of 3.3 million Polish Jews (91%); 900,000 of 1.1 million in Ukraine (82%); and 50–90% of the Jews of other Slavic nations, Germany, France, Hungary, and the Baltic states. Sephardi communities suffered similar depletions in a few countries, including Greece, the Netherlands and the former Yugoslavia. Many of the surviving Ashkenazi Jews emigrated to countries such as Israel, Australia, and the United States after the war.

 

Relationship to Other Jews

The term Ashkenazi also refers to the nusach Ashkenaz (Hebrew, "liturgical tradition", or rite) used by Ashkenazi Jews in their Siddur (prayer book). A nusach is defined by a liturgical tradition's choice of prayers, order of prayers, text of prayers and melodies used in the singing of prayers. Two other major forms of nusach among Ashkenazic Jews are Nusach Sphard (not to be confused with Sephardi), which is the same as the general Polish (Hasidic) Nusach; and Nusach Chabad, otherwise known as Lubavitch Chasidic, Nusach Arizal or Nusach he'Ari.

This phrase is often used in contrast with Sephardi Jews, also called Sephardim, who are descendants of Jews from Spain and Portugal. There are some differences in how the two groups pronounce Hebrew and in points of ritual.

Several famous people have this as a surname, such as Vladimir Ashkenazi. Ironically, most people with this surname are in fact Sephardi, and usually of Syrian Jewish background. This family name was adopted by the families who lived in Sephardi countries and were of Ashkenazic origins, after being nicknamed Ashkenazi by their respective communities. Some have shortened the name to Ash. Other spellings exist, such as Eskenazi by the Syrian Jews who relocated to Panama and other South-American Jewish communities.